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S-苯基-L-半胱氨酸合成的反应动力学及反应机理的研究 被引量:2

Study on Reaction Kinetics and Mechanism of Synthesis of S-phenyl-L-cysteine
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摘要 运用过量浓度法和微分法研究合成S-苯基-L-半胱氨酸的反应速率随反应物浓度变化的规律,确定了S-苯基-L-半胱氨酸合成反应的速率常数和反应级数,建立了反应速率方程,同时探讨了反应机理,为进一步优化反应条件提供了理论基础,并且通过实验找到了反应的最佳条件。 The methods of excessive concentration and differential coefficient were used to study the reaction rate change of synthesis of S-phenyl-L-cysteine with reactant concentration. The reaction rate constant and reaction order of the synthesis of S-phenyl-L-cysteine were found and reaction rate equation was established. The mechanism of the reaction was discussed providing the knowledge for further optimizing the reaction, and through experiment to find a best condition.
出处 《化学世界》 CAS CSCD 北大核心 2007年第5期257-261,共5页 Chemical World
关键词 S-苯基-L-半胱氨酸 苯胺重氮盐 紫外分光光度法 反应动力学方程 反应机理 S-phenyl-L-cysteine phenylamine diazonium salt ultraviolet spectrophotometry reaction kinetic equation mechanism
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参考文献7

  • 1Marzoni G,Kaldor W,Anthony J,et al.A convenient,large scale synthesis of N-Cbz-(S-phenyl)-L-cysteine[J].Syn Corn,1995,25(16):2475-2482.
  • 2Wolfe S,Kazmaier P M,Auksi H.Cyclization of cysteinylglycine sulfoxide under pummer reaction conditions[J].Can J Chem,1979,57(3):2412-2415.
  • 3Zbarsky S H,Young L.The synthesis of phenyl-L-cysteine and L-phenylmercapturic acid[J].J Biol Chem,1943,151:212-215.
  • 4Doodman L,Leonard O R,Baker B R.Poteintial anticancer agents.some sulflur-substrituted derivatives of cysteine[J].J Org Chem,1958,23:1251-1257.
  • 5Rajesh K D,Taylor E W,Robert S P.S-Aryl-L-cysteine S,S-dioxide:desige,synthesis,and evaluation of a new class of inhibitors of kynureninase[J].J Am Chem Soc,1993,115:1264.
  • 6Sasaki N A,Hashimoto C,Potier P.A novel approach to the synthesis of optically pure non protein a-amino acids in both land D configurationd from L-strine[J].Tetrahedron Letters.1987,28(48):6069-6079.
  • 7汪明芳,王娟娟,张关永.Cu(I)-L-半胱氨酸强酸性体系配合物组成的研究[J].化学世界,2007,48(2):65-67. 被引量:1

二级参考文献4

  • 1Wolfe S,Kazmaier P M,Auksi H.Cyclization of cysteinylglycine sulfoxides under pummerer reaction conditions[J].Can J Chem,1979,57(3):2412-2425.
  • 2Stricks W,Kolthoff I M.Polarographic investigations of reactions in aqueous solutions containing copper and cysteine (cystine).I.Cuprous copper and cysteine in ammoniacal medium.The dissociation constant of cuprous cysteinate Ⅱ.Reations in ammoniacal medium in the Presence and absence of sulfite[J].J Am Chem Soc,1951,73(3):1723-1733.
  • 3Pena M J,Alarcón I,López V.Electrochemical study of Cu (Ⅱ)-cysteine complexes in aqueous solution[J].Electrochim Acta,1990,35(1):47-53.
  • 4Deford D D,Hume D N.The determination of consecutive formation constants of complex Ions from polarographic data[J].J Am Chem Soc,1951,73(4):5321-5323.

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