小剂量芬太尼复合罗哌卡因用于分娩镇痛时对脐血血气分析的影响

Effect on cord blood gas analysis in fentany application of delivery analgesia

目的研究芬太尼用于分娩镇痛时对脐血血气分析结果及对产程、母婴的影响。方法120例产妇随机分为镇痛组和对照组;镇痛组60例,采用0.125%罗哌卡因复合芬太尼2μg/ml产妇自控硬膜外镇痛（PCEA）;对照组60例,为同期未实行镇痛的正常分娩者。比较两组产妇脐动、静脉血血气分析、SBP、DBP、HR、SaO2、、总产程（第一第二产程时间）、新生儿Apgar评分、视觉模拟评分（VAS）。结果①两组新生儿脐血血气分析指标测定值均在正常范围。总产程比较,差异无统计学意义;②两组产妇新生儿出生后1、5 min Apgar评分均为8分以上;③镇痛药起效后产妇疼痛明显减轻,宫缩时仅感腹部发紧发胀,双下肢无麻木感,活动自如。两组产妇VAS在镇痛前后差异有统计学意义（P〈0.05）。结论论芬太尼复合罗哌卡因用于分娩镇痛效果可靠,不延长产程,对新生儿无不良影响。

Objective To observe the effect on cord blood gas analysis,baby and mother in fentany application of delivery analgesia. Methods One hundred and twenty puerpera were divided into two groups, analgesia group and control group, the analgesia group,60 patients, were given 0. 125% ropivacaine combined with Fentany 2 μg/ml in PECA;the control group,60 patients, were nomal delivery without analgesia in the same time . The gas analysis on umbilical artery and umbilical vein, SBP, DBP, HR, SaO2, tolal stage of labor （ the first and the second stage） , newborn Apgar scores, VAS were compared . Results ①The cord blood gas analgesia in two group was among normal range . The tolal stage of labor had no significant difference ;②One and five rain Apgar scores after newborn birth were more than 8 ;③The pain was severely lessened after given analgesia and swelling Was feeled while uterine contraction and numbness wasn＇t reeled in the lower limbers. Vas had significant difference （ P 〈 0.05 ）. Conclusion Ropicacaine combined Fentany has effect on delivery analgesia and would not prolong the labor stage and has no harmful effects on newborn.