摘要
叶形态发生从射击顶端分生组织(SAM ) 在原基开始以后要求近轴离开轴心的极性的建立。抄写因素的几个家庭被知道在支持近轴或离开轴心的叶命运起关键作用。最近， post-transcriptional 基因 silencing 小径被显示了调整叶极性的建立，提供进叶开发的新奇、令人激动的卓见。例如， microRNAs (miR165/166 ) 和交易的 siRNA (导出 TAS3 的 tasiR-ARF ) 被显示了镇压几关键抄写因素基因的表示。另外，规定的另一水平， translational 以后规定，最近被研究在叶极性在 26Sproteasome 的角色上揭示了。尽管我们关于位于近轴离开轴心的极性的建立下面的分子的机制的理解极大地改善了，仍然有大部分，留下逃犯。这评论试图讨论最近的进步，以及留下的问题，关于位于叶极性形成下面的分子的机制。
Leaf morphogenesis requires the establishment of adaxlal-abaxlal polarity after primordium initiation from the snoot apical meristem （SAM）. Several families of transcription factors are known to play critical roles in promoting adaxial or abaxial leaf fate. Recently, post-transcriptional gene silencing pathways have been shown to regulate the establishment of leaf polarity, providing novel and exciting insights into leaf development. For example, microRNAs （miR 165/166） and a trans-acting siRNA （TAS3-derived tasiR-ARF） have been shown to repress the expression of several key transcription factor genes. In addition, yet another level of regulation, post-translational regulation, has been revealed recently by studies on the role of the 26S proteasome in leaf polarity. Although our understanding regarding the molecular mecha- nisms underlying establishment of adaxial-abaxial polarity has greatly improved, there is still much that remains elusive. This review aims to discuss recent progress, as well as the remaining questions, regarding the molecular mechanisms underlying leaf polarity formation.
基金
supported by grants from the National Natural Science Foundation of China(Nos.30630041,90208009)
the Ministry of Science and Technology of China(No.04JC14077)
the Shanghai Scientific Committee(No.KSCX2-YW-N-016)to H Huang.
