肝硬化病人血清sIL-2R测定及临床意义

THE SERUM SOLUBLE IL-2 RECEPTOR IN CIRRHOSIS OF THE LIVER

该文对57例肝硬化病人血清sIL－2R测定，结果显示：肝硬化病人血sIL－2R较正常对照组明显增高（P＜0．05）、且与Child－Pugh分级有关；HBsAg阳性者较HBsAg阴性者升高明显（P＜0．01），合并肝癌老较未并发者升高显著（P＜0．001）。提示血清sIL－2R测定可作为肝硬化免疫失衡的重要指标；对病情和预后的判定亦有帮助。

The serum soluble interleukin - 2 receptor (sIL- 2R) Ievels were measured in 57 patients with cirrhosis of theliver. The level of sIL - 2R found in the hepatic cirrhosis group was higher than that of the control group, correlating with Cheld - Pugh scores. The highest sIL - 2R levels were found in patients with negative, HBsAg, and in Patients with hepatic cirrhosis complicated with hepatocellular carcinoma, indicating that the levels of sIL - 2R can beused as an indicator of an imbalance in the immune system of a patient with cirrhosis of the liver. The sIL - 2R Ievels can be useful in predicting the outcome and development of hepatic cirrhosis.