摘要
Objective To repair segmental mandibular defects with autologous bone marrow stromal cells （BMSCs） engineered bone.Methods Isolated BMSCs were expanded in vitro and osteogenic induced.In 12canines,a 3cm segmental mandibular defect at right mandible was created.6 canine＇s defects were repaired with cell-scaffold constructs made from induced BMSCs and coral;others were repaired with coral as control.
