良性前列腺增生TURP术后病理诊断前列腺癌27例分析

Analysis of prostatic cancer diagnosed by pathology after TURP of BPH(A report of 27 cases)

目的探讨前列腺增生症病人经尿道前列腺电切(TURP)术后病理检出前列腺癌的临床特点及治疗措施。方法对三家医院于2003年1月～2006年12月经尿道前列腺电切术(TURP)327例进行回顾性分析,对比术后病理诊断为前列腺癌的患者与前列腺增生的患者的前列腺抗原及前列腺特异性抗原密度(PSAD)。结果327例患者中PSA在4～10ng/ml间者共112例,PSA在10～20ng/ml之间者共15例。术后病理诊断为前列腺癌的27例,其中有21例患者的PSAD值高于0.15。结论经尿道前列腺电切术(TURP)是早期发现前列腺癌的重要手段;前列腺特异性抗原密度(PSAD)有助于更好地鉴别前列腺增生症和前列腺癌。

Objective To study the clinical feature and therapeutic measure detected prostatic cancer by pathology after TURP of BPH. Methods From January 2003 to December 2006,327 cases received TURP were analyzed retrospectively. And postoperative pathologic diagnosis as prostatic cancer and BPH were compared in the prostate specific antigen （PSA） and prostate specific antigen density（PAD）. Results Among the 327 cases, the PSA was 4- 10 ng/ml, 10-20 ng/ml in 112 and 15 cases respectively. Postoperative pathologic diagnosis as prostatic cancer was in 27 cases and among them, the value of PSAD was more than 0.15 in 21 cases. Conclusion TURP is an important measure for early diagnosis of prostatic cancer. PSAD examination would contribute to differentiate prostatic hyperplasia and prostatic cancer.