150例新生儿高胆红素血症临床分析

Etiological analysis and treatment with 150 hyperbilirubinemia of newborn

目的:分析150例新生儿高胆红素血症患儿的病因及治疗方法。方法:对150例新生儿高胆红素血症的病因、发病年龄、治疗、转归进行回顾性分析。结果:新生儿高胆红素血症的病因依次为围产因素、母乳性黄疸、感染因素及其它因素。应用蓝光照射是150例新生儿高胆红素血症的主要治疗手段,光疗前胆红素平均值为(18.65±5.39)mg/dl、平均照射(4.83±2.57)天后降为(11.92±7.63)mg/dl。结论:新生儿高胆红素血症的病因以围产因素为主(32.0%),其次是母乳性黄疸(27.3%)、感染因素(26.0%)。至今为止,蓝光照射是新生儿高胆红素血症治疗的首选方法,结合其发病的相关因素辅以中西药治疗对新生儿高胆红素血症疗效显著。

Objective： To summary the etiological factors and treatments of 150 cases of neonatal hyperbilinthinaemia. Methods： The etiological factors, age and treatment of 150 cases of neonatal hyperbilirubinaemia were analyzed retrospectively. Results： The pathogeny of neonatal hyperbilirubinaemia were as following： perinatal factors, infection, breast milk jaundice, hemolytic disease and other causes. Blue phototherapy was the major treatment of 150 cases of neonatal hyperbilinthinaemia. The average values of bilirubin before blue phototherapy were （18. 65±5. 39） mg/dl, after an average time of blue phototherapy were （4. 83±2. 57） d, the values decreased to （11. 92 ±7. 36） mg/dl. Conclusion： The pathogenies of neonatal hyperbilirubinaemia, perinatal factors are the most common （32%）, followed by breast milk jaundice （27. 3% ）, and infections （26%）. Up till now the blue phototherapy is still the best choice. According to the appropriate etiological factors combined application of treatments with traditional Chinese medicine and Western medicine together have good therapeutic effect on the neonatal hyperbilirubinaemia.