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未变性乳清蛋白对支气管哮喘儿童红细胞抗氧化酶系统的影响

Antioxidative protective effect of undenatured whey protein on asthma children's erythrocyte
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摘要 目的:观察未变性乳清蛋白对支气管哮喘儿童抗氧化酶系统的影响。方法:采集30例健康儿童血标本;收集56例哮喘患儿资料,随机分为治疗组30例,采用未变性乳清蛋白加普米克(布地奈德气雾剂)治疗;对照组26例,单用普米克治疗。分别测定健康儿童、对照组及治疗组儿童红细胞浆内总谷胱甘肽(GSH)含量及谷胱甘肽过氧化物酶(GSH-PX)活性。结果:支气管哮喘儿童红细胞总GSH含量较健康儿童减少,GSH-PX活性降低;治疗组较对照组红细胞GSH含量及GSH-PX活性有明显提高。结论:未变性乳清蛋白能有效提高支气管哮喘患儿红细胞浆中GSH水平,增加GSH-PX活性。 Objective: To investigate the antioxidative effect of undenatured whey protein on asthma children's erythrocyte. Methods: Arterial blood sample were taken from 30 healthy children. 56 asthma children's information were collected and randomly divided into two groups: the treatment group had 30 cases which were given undenatured whey protein and Pulmicort (Budesonide Aerosol), the control group had 26 cases which were given Pulmicort . Cord blood samples of healthy children and two groups of asthma children were taken to determine reduced glutathione (GSH) and activity of glutathione peroxidase ( GSH - PX) in erythrocyte intracytoplasm. Results : Reduced glutathione and activity of glutathione peroxidase in asthma children were lower than that in healthy children, and the treatment group's were higher than the control group's. Conclusion : Reduced glutathione and activity of glutathione peroxidase with undenatured whey protein are increased.
出处 《中国妇幼保健》 CAS 北大核心 2007年第18期2504-2505,共2页 Maternal and Child Health Care of China
关键词 未变性乳清蛋白 谷胱甘肽 红细胞 支气管哮喘 Undenatured whey protein Glutathione Red blood cell Bronchial asthma
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参考文献7

  • 1诸福棠.实用儿科学.第7版,北京:人民卫生出版社,2004:42
  • 2Klinika Pediatrii,Chorob Pluc I Reumatologii AM w Lublinie.拼写问题 Selected parameters of the oxidative-antioxidative balance in children with bronchial asthma exacerbations.Pol Merkuriusz Lek,2001Nov,11 (65):358
  • 3Fenech AG,Ellul-Micallef R.Selenium,glutathione peroxidase and superoxide dismutase in maltese asthmatic patients:effect of glucocorticoid administration.Pulm Pharmacol Ther,1998,11 (4):301
  • 4Bounous G,Gold P.The biological activit of undenatured dietary whey proteins:role of glutathione.Clin Invest Med,1991 Aug,14 (4):296
  • 5Nadeem A,Chhabra SK,Masood A et al.Increased oxidative stress and altered levels of antioxidants in asthma J Allergy Clin Immunol,2003Jan,111 (1):72
  • 6Micke P,Beeh KM,Schlaak JF et al.Oral supplementation with whey proteins increases plasma glutathione levels of HIV-infected patients.Eur J Clin Invest,2001,31:171
  • 7Kennedy RS,Konok GP,Bounous G et al.The use of a whey protein concentrate in the tratment of patients with metastatic carcinoma:a phase Ⅰ-Ⅱ clinical study.Anticancer Res,2002,15 (3):264

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