1NHLBI/WHO workshop.Global Iniciative for Asthma(GINA).Global strategy for asthma management and prevention.Bethesada:National Institutes of Health,National Heart,Lung and Blood Institute.Publication number,1995,95:3659.
2Bateman ED,Boushey HA,Bousquet J,et al.Can guidelinedefined asthma control be achieved The Gaining Optimal Asthma Control study.Am J Respir Crit Care Med,2004,170:836-844.
3Rabe KF,Adachi M,Lai CK,et al.Worldwide severity and control of asthma in children and adults:the global asthma insights and reality surveys.J Allergy Clin Immunol,2004,114:40-47.
4Vignola AM,Chanez P,Campbell AM,et al.Airway inflammation in mild intermittent and in persistent asthma.Am J Respir Crit Care Med,1998,157:403-409.
5Chetta A,Foresi A,Del Donno M,et al.Airways remodeling is a distinctive feature of asthma and is related to severity of disease.Chest,1997,111:852-857.
6Barnes PJ.Inhaled glucocorticoids for asthma.N Engl J Med,1995,332:868-875.
8Barnes PJ.Scientific rationale for inhaled combination therapy with long acting beta 2 agonists and corticosteroids.Eur Respir J,2002,19:182-191.
9Mrrray JJ,Church NL,Anderson WH,et al.Concurrent use of salmeterol with inhaled corticosteroids is more effective than inhaled corticosteroid dose increases.Allergy Asthma Proc,1999,20:173-180.
1National Institutes of Health,National Heart,Lung,and Blood Institute.National Asthma Education and Prevention Programme.Expert Panel Report:Guidelines for the diagnosis and management of asthma update on selected topics 2002.J Allergy Clin Immunol,2002,110 (5 Suppl):S142-219.
2Martin RJ,Szefler SJ,Chinchilli VM,et al.Systemic effect comparisons of six inhaled corticosteroid preparations.Am J Respir Crit Care Med,2002,165(10):1377-1383.
3Szefler S J,Martin RJ,King TS,et al.Significant variability in response to inhaled corticosteroids for persistent asthma.J Allergy Clin Immunol,2002,109(3):410-418.
4Drazen JM,Silverman EK,Lee TH.Heterogeneity of therapeutic responses in asthma.Br Med Bull,2000,56 (4):1054-1070.
8Hensen C,Suter A,Lerch E,et al.Suppression and recovery of adrenal response after short-term,high-dose glucocorticoid treatment.Lancet,2000,355 (9203):542-545.
9Abdu TA,Elhadd TA,Neary R,et al.Comparison of the low dose short synacthen test (1 microg),the conventional dose short synacthen test (250 microg),and the insulin tolerance test for assessment of the hypothalamo-pitutitary-adrenal axis in patients with pituitary disease.J Clin Endocrinol Metab,1999,84(3):838-843.
10Nielsen LP,Dahl R.Therapeutic ratio of inhaled corticosteroids in adult asthma:a dose-range comparison between fluticasone propionate and budesonide,measuring their effect on bronchial hyperresponsiveness and adrenal cortex function.Am J Respir Crit Care Med,2000,162(6):2053-2057.