急性重型颅脑损伤患者应用亚低温治疗的临床观察

Clinical research of applying mild hypothermy to cure patients of acute severe craniocerebral injury

目的观察亚低温对急性重型颅脑损伤患者的临床治疗效果。方法本组64例患者,随机分为亚低温治疗组32例,均于伤后24 h内行亚低温治疗,对照组32例,直肠温度控制在36.5℃～37℃,其他治疗同亚低温组。2组病人于伤后3个月时根据GOS评估法判定疗效。结果亚低温治疗效果优于常规治疗。结论对重型颅脑损伤患者在综合治疗的基础上早期行亚低温治疗可明显减少其死亡率和改善预后。

Objective To study the clinical therapeutic efficacy of mild hypothermy to cure patients with acute severe craniocerebral injury. Mechods 64 patients were divided into the mild hypothermy treatment group who were treated after 24 hours and the control group of 32 cases whose rectum temperature was controlled between 36. 5 to 37℃. Two groups of patients＇ therapeutic efficacy was compared according to the GOS valuation method 3 months after their injury. Results The therapeutic efficacy of the mild hypothermy treatment group was better than that of the control group. Conclusion The mortality could be reduced and the prognosis could be improved obviously in the severe craniocerebral injury patients who would be treated under the mild hypothermy combined with the basic treatment in the early time.