罗红霉素联合布地奈德气雾剂治疗支气管哮喘的疗效观察

Observation of effects of asthmatic patients treated with roxithromycin combined with budesonide aerosol

目的观察罗红霉素辅佐布地奈德气雾剂治疗支气管哮喘的临床疗效以及对诱导痰中炎性细胞变化的影响。方法50例门诊支气管哮喘患者分为2组:布地奈得气雾剂治疗组为A组,罗红霉素联合布地奈德气雾剂治疗组为B组,比较其治疗前后临床症状及诱导痰中炎性细胞的变化。结果与A组相比,B组治疗后哮喘患者发作次数,病情程度,肺功能检查均明显减轻(P<0.05),诱导痰中炎性细胞变化亦显著减少(P<0.05)。结论罗红霉素联合布地奈德气雾剂治疗支气管哮喘能取得较好的疗效。

Objective To observe the clinical efficiency and influence of inflammatory cells in the induced sputum of asthmatic patients treated with roxithromycin combined with budesonide aerosol. Methods 50 eases with asthma were clinically devided into two groups： Group A treated with budesonide aerosol and group B treated with roxithromyein combined with budesonide aerosol. Changes of the clinical efficiency and influence of inflammatory cells in induced sputum were analysed. Results Compared with group A,the onset frequency,the severity and pulmonary function test in group B were rellieved obviously. They were statistically significant （P〈0. 05）. The inflammatory cells in the induced sputum was decreased obviousely（P〈0.05）. Conclusion Asthmatic patients treated with roxithromycin combined with budesonide aerosol have better therapeutic effects.