浙江省金华市2007年普通高校招生体检中ALT异常的结果分析

ANALYSIS ON ABNORMAL INCREASE OF ALT IN HIGHER SCHOOL ADMISSION CHECK-UP IN JINHUA OF ZHEJIANG PROVINCE IN 2007

[目的]通过10534例浙江省金华市高校考生体检中丙氨酸氨基转移酶(ALT)阳性检出率,对高校考生ALT增高的原因进行分析。[方法]ALT测定方法为紫外乳酸脱氢酶法(LDH-UV法),仪器为SYSMEX-180全自动化分析仪,试剂为SYSMEX公司生产,正常值为0IU/L～50.0IU/L。[结果]检查高校考生体检者10534例,ALT增高者411例,占3.90%,由乙型肝炎病毒导致的120例,占29.20%,其他原因的291例,占70.80%。而291例当中由营养补品导致的占31.27%,血脂增高导致的占38.14%。[结论]研究显示我市乙肝疫苗计划免疫比较成功,乙肝阳性率明显降低。但血清ALT异常增高,其中营养补品、脂肪肝对肝脏功能损害的比例较高,应引起足够重视。

[Objective] To analyze the rcason for the increase of ALT of positive alanine aminotransferase students in 10534 examinees who took part in university admission check-up in Jinhua of Zhejiang province. [ Methods] The method of LDH-UV was used to determine the level of ALT, the apparatus was SYSMEX-180 automatic analyzer and the reagemt was produced by SYSMEX Company. The normal value of ALT is 0 IU/L-50.0IU/L. [Results] 10 534 students whe cook part in university entrance examination were examined. 411 of them had a higher level of ALT, accounting tot 3.9%. 120 cases were caused by hepatitis B virus （29.20%） and 291 cases were caused by other factors （70.80%）, among which 31.27% was caused by tonics, 38.14% was caused by the increase of blood lipid. [Conclusions] The results show that the implementation of hepatitis B immunization program in Jinhua is successful, the positive rate of hepatitis B decreases greatly. But the ALF in blood serum abnormally increases. The percentages of the damage to liver function caused by tonics, fatty liver, are comparatively higher, which we should attach great importauce to.