吡啶羧酸铬对肥育猪皮下脂肪组织脂肪酸合成酶mRNA表达的影响

Effects of Chromium Picolinate on mRNA Expression of Fatty Acid Synthase in Subcutaneous Adipose Tissue of Finishing Pigs

选用体重58 kg左右的斯格×斯格×杜洛克三元杂交肥育猪48头,按试验要求分成2组,每组3个重复,分别饲喂添加0、200μg/kg吡啶羧酸铬的玉米-豆粕型饲粮。结果表明,吡啶羧酸铬能明显改善肥育猪的胴体组成,胴体瘦肉率提高了6.1%(P<0.05),眼肌面积增大了13.4%(P<0.05),胴体脂肪率和平均背膘厚分别降低了13.5%(P<0.05)、11.1%(P<0.05);皮下脂肪组织FAS mRNA丰度减少了23.9%(P<0.05),FAS活性降低了19.4%(P<0.05)。提示吡啶羧酸铬可通过降低肥育猪皮下脂肪组织FAS的mRNA表达及其活性,从而减少脂肪沉积,改善胴体组成。

Forty-eight finishing pigs（Seghers × Seghers × Duroc）weighing about 58 kg are divided into two groups, each with three replicates of eight pigs（four barrows and four gilts）per replicate, and fed with corn-seybean meal basal diets supplemented with chromium pieolinate at 0 or 200 μg/kg feed. The results show that Chromium Pieolinate can significantly improve carcass composition. Carcass lean percentage and longissimus muscle area are increased by 6.1% （P〈0.05）and 13.4% （P〈0.05） respectively; carcass fat percentage and average baekfat thickness are decreased by 13.5% （P〈0.05）and 11.1% （P 〈0.05） respectively; mRNA abundance and enzyme activity for FAS in subcutaneous adipose tissue are also decreased by 23.9% （P〈 0.05）and 19.4%（P〈0.05）respeetively. This study suggests that Chromium Pieolinate can reduce fat deposition via a decrease in adipose tissue FAS mRNA expression and its activity, thus resulting in an improvement of carcass characteristics.