艾达乐治疗外生殖器尖锐湿疣临床疗效观察

Clinical observation for treatment effects of topical 5% imiquimod (Aldara) to external genital condyloma acuminatum

目的观察5%咪喹莫特乳膏治疗外生殖器尖锐湿疣的疗效和安全性。方法5%咪喹莫特乳膏治疗45例外生殖器尖锐湿疣患者8周,分别于第2、4、6、8周末观察治疗效果和不良反应。结果42例患者完成治疗,基本治愈率为42.9%,有效率达97.6%。男女患者基本治愈率无显著性差异。不良反应发生率73.3%。最常见的不良反应为局部轻度红肿、糜烂。结论5%咪喹莫特乳膏可有效治疗外生殖器尖锐湿疣,不良反应较轻,男女患者疗效无显著差异。

Objective To observe treatment effects and security of topical 5% Imiquimod cream to external genital warts. Methods Forty-five patients of external condyloma acuminatum were treated with topical 5 % irniquimod cream for 8 weeks. The treatment effects and side effects were observed respectively at the end of 2, 4,6 and 8 weeks. Results Forty-two patients finished whole treatment. The healing rate was 42.9%, and effective rate was 97.6%. There was no remarkable difference between the healing rates of male and female patients. The side effects rate was 73.3 %. The most often side effects were local mild erythema and erosion. Conclusion With mild side effects, 5 % imiquimod cream is effective to external condyloma acuminatum. There is no effect difference between male and female patients.