摘要
本文利用尾静脉注射四氧嘧啶90mg/kg致糖尿病小鼠模型,研究了老头草半仿生提取物(LSBE)的降血糖作用,测定了LSBE对正常和糖尿病模型小鼠的血糖(Glu)、胆固醇(Chol)、甘油三酯(TG)、血清胰岛素(Ins)和胰淀粉酶(Amy)的影响。结果显示LSBE可使正常及模型小鼠血糖明显降低,并发现治疗8d后四氧嘧啶模型小鼠Ins、TG升高,Amy降低。
Effects of semi-bioni extract of L.leontopodiodes （LSBE） on the blood glucose （ Glu）, triglyceride （TG）, cholesterol（Chol） and pancreatic amylace of normal and diabetic mice induced by alloxan were studied. The results showed that the blood Glu,TG and insulin of alloxan-treated mice were increased significantly. LSBE could reduce the blood glucose of normal and alloxan-induced diabetic mice. But no observed effects of LSBE were found on blood TG, Chol and Amy of normal and diabetic mice.
出处
《天然产物研究与开发》
CAS
CSCD
2007年第3期508-510,共3页
Natural Product Research and Development
关键词
老头草
半仿生提取法
糖尿病
血糖
胰岛素
L. leontopodlodes
semi-bionic extraction
diabetic
blood glucose
insulin
