聚乙二醇催化下的反常Reimer-Tiemann反应

The Behavior of Reimer-Tiemann Reaction Under the Catalysis of PEG

自1876年Reimer-Tiemann反应(以下简称R-T反应)提出后,许多化学工作者曾对该反应进行了深入研究。1988年丁新腾等又报道了叔胺存在下的反常R-T反应。但以聚乙二醇(PEG)为相转移催化剂,催化R-T反应未见报道。本文报道了无水相存在下PEG催化的反常R-T反应,并对其催化行为从理论上进行了探讨。

Reimer-Tiemann reaction under phase transfer catalysis of poly (ethylene glycols) (PEG) has been studied. It has been shown that PEG have an obvious catalytic effect on the reaciton and the ratio of the para- and ortho-products is abnormal. Such an abnormal Reimer-Tiemann reaction has not been reported in literature. The conditions of the abnormal Reimer-Tiemann reaction were studied in detail and a mechanism was proposed.