胃幽门螺杆菌感染与口臭关系的初步研究

The relationship of halitosis and Helicobacter pylori

目的:探讨胃幽门螺杆菌感染与口臭的关系。方法:选择无牙周疾病和全身疾病(上消化道疾病除外)的受试者50例,在胃镜检查或呼气试验前进行口臭测试及口腔相关指标检查,然后进行胃镜活检和呼气试验检测胃内幽门螺杆菌感染情况。使用SPSS11.5对数据进行统计学分析。结果:50例受试者经鼻测法测试有口臭28例,无口臭22例,各项牙周指标表明,受试者均牙周健康。χ2检验表明,有、无口臭的受试者中,幽门螺杆菌的阳性率分别为57.1%和18.2%,差异具有统计学意义(P<0.01)。Logistic回归方程显示,胃内幽门螺杆菌感染是方程中唯一有统计学意义的变量(P<0.05)。结论:幽门螺杆菌可能与牙周健康者的口臭有关。

PURPOSE： The aim of the study was to investigate the relationship between halitosis and Helicobacter pylori infection in stomach, METHODS： Fifty subjects without periodontal diseases and systematic disease （exclude gastrointestinal diseases） were included. Infection of H.pylori was diagnosed by biopsy and ^14C-urea breath test. SPSS11.5 software package was used to analyze the data. RESULTS： All the subjects were periodontal healthy according to the periodontal index. The prevalence of H, pylori infection in halitosis subjects was significantly higher than that in the normal subjects （57.1% VS 18,2%, P〈0.01）. Logistic regression analysis showed that H.pylori was the only significant variable in the equation（P〈0.05）, CONCLUSIONS： H,pylori in stomach may be involved in the presence of halitosis in periodontal healthy subjects.