摘要
报告1991年12月~1995年12月用立体定向对脑深部肿瘤142例进行了铱192后装管置入作了间质内放疗。男106例,女36例,年龄5~77岁,平均35.9岁。术后120例随访1~4年,平均2.2年,结果显示:平均生存期26个月,比未经间质内放疗者平均13个月显著延长,证明铱-192瘤内放疗是治疗脑深部肿瘤一种可行有效的方法。
CT Guided stereitactic procedures make it easy to place radioactive material in tumors at exact and reproducible sites. A stereotactic program of interstitial iridium 192 radiotherapy in deep seated brain tumors has been applied in 142 cases since December 31, 1992. There were 106 males and 36 females ranging in age from 5 77 years (median 35.9 years). Primary and recurrent tumor sites included the frontal lobe (29), parietal lobe (26) temporal lobe (15), frontoparietal region (20), temporo parietal region (18), parieto occipital region (15), occipital lobe (5) frontotemporal region (13) and cerebellar (2). Stereotactic biopsy were astrocytoma in 80 cases, glioblastoma in 13, oligodendroglioms in 5, ependyma in 2, metastasis in 12, lymphoma in 2, meningicma in 4 pinealocytoma in 13, craniopharyngioma in 5, chordoma in 2, colloid cyst. in 1, engioneoplasm in 1 and medulloblastoma in 2. 120 Patients were up foolowed from 1 to 4 years, with a median of 2, 2 years. Our results showed that the median survival of this group of patients was 26 months which was significantly higher than the mediansurvival of 13 months for a group of similar patients treated whthout an Important boost.
关键词
脑肿瘤
深部肿瘤
立体定向
近距离照射
Brain deep
Seated tumour
Stereotactic interstitial radiotherapy
( Original article on page 7)