脑立体定向手术治疗慢性精神分裂症的近期与远期疗效

Recent and long term curative effect of brain stereoencephalotomy for chronic schizophrenia

采用脑立体定向手术治疗慢性精神分裂症。术后对３８例病人随访５～１０年，近期临床疗效及量表评定有效率分别为７６．３％与７８．５％，远期有效率分别为５０％与５７．１％。其中淡漠、退缩、思维障碍无显著改善；激活性高、敌对猜疑改善较为明显。８例韦氏智力测验、临床记忆量表测验的病人脑功能与术前持平。

To evaluate the near ang far curative effect of brain stereoencephalotomy for chronie schizophrenia. Method: 38 objects were followed up for 5 10 years after surgery who is on the basis of clinical symptoms and BPRS to evaluate the curative effect. Results: The improvement rate of near curative effect were 76.32% in clinical symptoms and 78.5% in scale evaluation, of far curative effect were 50% and 57.14% respectively. The symptoms of apathy cower, disordor of though had no significant improvement, but the symptoms of activiation, hostility and suspicion ameliorated evidently. 8 subjects who received the test of WAIS, and Clinical Memory Scale had the same mental function as before surgery. Discussion: The brain stereoencephalotomy is one of the therapies for schizophrenia which is effective and safe.