期刊文献+

早发型与晚发型重度子痫前期不同妊娠结局的比较分析 被引量:2

下载PDF
导出
摘要 目的:探讨早发型与晚发型重度子痫前期的不同妊娠结局。方法:将159例重度子痫前期患者根据发病孕周分为4组,A组,<28周,10例;B组,28~31周,20例;C组,32~33周,16例;D组,≥34周,113例。观察4组孕妇入院时血压、尿蛋白定量、发病孕周、终止妊娠孕周、保守治疗时间、母儿并发症。结果:A、B组入院时血压及24h尿蛋白定量明显高于C、D两组,差异具有显著性意义(P<0.05),4组孕妇发病孕周、分娩孕周之间差异有极显著性意义(P<0.01)。在保守治疗时间上,D组时间最短,B组治疗时间最长,与其他组比较,差异具有显著性意义(P<0.05)。在孕产妇并发症中,A组患者中多器官同时受损的发生率最高,D组并发症发生率最低,与其他组相比,差异具有显著性意义(P<0.05)。B组中围产儿生长受限、低出生体重、胎儿窘迫、新生儿窒息发生率明显高于C、D组,差异具有显著性意义(P<0.05),但C、D两组相比,差异无显著性意义(P>0.05)。结论:早发型重度子痫前期与晚发型相比,孕妇起病时间早,程度重,有较多并发症,容易发生多器官功能同时受损。孕32周前围产儿较易发生胎儿生长受限、低体重儿、胎儿窘迫、新生儿窒息。而孕32周之后围产儿病率及死亡比与孕34周之后并无明显差异。
出处 《实用医学杂志》 CAS 2007年第12期1838-1840,共3页 The Journal of Practical Medicine
  • 相关文献

参考文献8

  • 1Sibai B M,Mercer B M,Schiff E,et al.Aggressive versus expectant management of severe preeclampsia at 28 to 32 weeks' gestation:a randomized controlled trial[J].Am J Obstet Gynecol,1994,171(8):818-822.
  • 2Hall D R,Odendaal H J,Steyn D W,et al.Expectant management of early onset severe preeclampsia:maternal outcome[J].BJOG,2000,107(10):1252-1257.
  • 3杨孜,李蓉,石凌懿,王丽娜,叶蓉华,王荣,黄萍.早发型重度先兆子痫的临床界定及保守治疗探讨[J].中华妇产科杂志,2005,40(5):302-305. 被引量:333
  • 4杨孜,叶蓉华.重度妊娠高血压综合征发生时间与母儿预后的关系[J].北京医科大学学报,1996,28(4):298-300. 被引量:28
  • 5Vigil De Gracia P,Montufar Rueda C,Ruiz J.Expectant management of severe preeclampsia and preeclampsia superimposed on chronic hypertension between 24 and 34 weeks'gestation[J].Eur J Obstet Gynecol Reprod Biol,2003,107 (1):24-27.
  • 6Begum M R,Akhter S,Begum A,et al.Conservative management of eclampsia and severe preeclampsia.A Bangladesh experience[J].Medscape Womens Health,2002,7 (1):11.
  • 7Odendaal H J,Pattinson R C,Bam R,et al.Aggressive or expectant management for patients with severe preeclampsia between 28 ~ 34 weeks' gestation:a randomized controlled trial[J].Obstet Gynecol,1990,76(9):1072-1075.
  • 8Withagen M I,Wallenburg H C,Steegers E A,et al.Morbidity and development in childhood of infants born after temporizing treatment of early onset preeclampsia[J].BJOG,2005,112(8):910-914.

二级参考文献14

  • 1杨孜,叶蓉华.重度妊娠高血压综合征发生时间与母儿预后的关系[J].北京医科大学学报,1996,28(4):298-300. 被引量:28
  • 2周瑾,中国实用妇科与产科杂志,1993年,9卷,219页
  • 3米粼,中华妇产科杂志,1993年,28卷,514页
  • 4郑怀美,妇产科学(第3版),1990年
  • 5金汉珍,实用新生儿学,1989年
  • 6田雪萍,高危妊娠的处理,1986年
  • 7Branch DW, Andres R, Digre KB, et al. The association of antiphospholipid antibodies with severe preeclampsia. Obstet Gynecol, 1989,73:541-545.
  • 8Sibai BM, Mercer BM, Schiff E, et al. Aggressive versus expectant management of severe preeclampsia at 28 to 32 weeks' gestation: a randomized controlled trial. Am J Obstet Gynecol,1994,171:818-822.
  • 9Hall DR, Odendaal HJ, Steyn DW, et al. Expectant management of early onest, severe pre-eclampsia: maternal outcome. BJOG ,2000,107:1252-1257.
  • 10Cunningham FC, Gant NF, Leveno KJ, eds. Williams Obstetrics. 21st ed. New York: McGraw-Hill ,2001. 569-570.

共引文献348

同被引文献19

  • 1徐永萍,刘立新,潘因,马德美,杨勇霞,亓向群,邱健青.低分子肝素治疗重度子痫前期患者效果的研究[J].现代妇产科进展,2006,15(1):54-56. 被引量:22
  • 2Sameshima H,Kodama Y,Ikenous T,et a1.Antithrombin improves fetal condition in women with severe pre-eclampsia before32weeks of gestation:a randomized,double-blind,placebo-controlled trial[J].Obstet Gynaecol Res,2008,34(1):34-39.
  • 3Rath W.Pre-eclampsia and inherited thrombophilia:a reappraisal[J].Semin Thromb Hemost,2011,37(2):118-124.
  • 4Von Dadelszen P,Magee LA.Subclaosification of preeclampsia[J].Hypertension in Pregnancy,2003,22(2):143-148.
  • 5Sibai B,DeLker G,Kupferminc M.Preeclampsia[J].Lancet,2005,365(9461):785-799.
  • 6Vaisbuch E,Romero R,Mazaki-Tovi S,et al.Retinol blinding protein4-a novel association with early-onset pre-eclampsia[J].J Perinat Med,2010,38(2),129-139.
  • 7Zeev B,Benjamin B. Thrombophilia -associated pregnancy wastage [J].Fertil Steril, 1999,5(72):765.
  • 8Kadyrov M, Kingdom JC, Huppertz B,Divergent trophoblas invasion and apoptosis in maternal anemia and earlt-onset preeclampsia in trauterine prowth restriction[J]. Am J Obstet Gynecol,2006,19(2): 5572-5631.
  • 9Marrei S,Ancel PY, Marpeau L, et aI. Neonatal and 5-year outcome aRer brith at 30-34 weeks of gestation[J].Obstet Gynecol ,2007,110(l):72-80.
  • 10Hall DR. Ealy pre-eclampsia what proportion of women qualify for expectant management and if not, whynot [J].Eur J Obstet Gynecol Reprod Biol, 2006,128 (122):169-174.

引证文献2

二级引证文献29

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部