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NOD2基因P268S突变是中国人克罗恩病的易感基因吗? 被引量：1

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摘要 本期龙靖华等作者发表的论文，采用聚合酶链反应（PCR）扩增NOD2／CARD15基因12对外显子．纯化后直接测序的方法，研究了我国广东地区48例克罗恩病（CD）患者、50例溃疡性结肠炎（UC）患者和50名健康对照者NOD2基因突变与炎症性肠病（IBD）的相关性，结果发现了一个有意义的现象。CD组NOD2P268S突变率显著高于UC组和健康对照组．且与CD患者的发病年龄、
作者 夏冰
机构地区 武汉大学中南医院消化系病研究中心
出处 《胃肠病学》 2007年第6期321-322,共2页 Chinese Journal of Gastroenterology
关键词 NOD2基因 易感基因 克罗恩病 基因突变 NOD2/CARD15 健康对照组 中国 聚合酶链反应
分类号 R574 [医药卫生—消化系统]
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参考文献1

二级参考文献14

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共引文献15

同被引文献32

引证文献1

二级引证文献35

胃肠病学
2007年 第6期

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