2004年深圳市部分中学生乙型肝炎病毒感染状况调查

Investigation on the State of HBV Infection of Middle School Students in Shenzhen in 2004

[目的]为制定深圳市龙岗区中学生乙型肝炎的防治措施。对1 620名中学生HBV感染状况及其影响因素进行了调查。[方法]用ELISA法对1 620名中学生的血清进行乙肝病毒五种标志物检测,对结果进行统计分析。[结果]HBsAg阳性89人,阳性率为5.49%;初中学生HBsAg的阳性率(4.24%)低于高中学生(7.04%),差异有统计学意义(P<0.05);男生感染率(6.67%)高于女生(4.13%),差异有统计学意义(P<0.05);有明确乙肝疫苗接种史的学生中未发现有HBsAg阳性者;HBsAg阳性的学生中,HBV-DNA阳性占53.93%,HBeAg阳性率为51.68%。[结论]通过对HBV感染影响因素的调查显示,HBV感染与家族乙肝病史、输血及血制品应用史有关。

[Objective]Investigation was carried out on HBV infection and infected factors for 1 620 students from middle schools,in order to make measures for HBV control and prevention in schools of Longgang district of Shenzheng municipality. [Methods]The sera＇s analysis of HBV infection of 1 620 students from middle schools were determined by ELISA. [Results]It indicated that 89 students were HBsAg positive,positive rate was 5.49 %. The positive rate in junior high students（4.24%） is less than that in senior high students（7.04%）. There was a significant difference （ P〈0.05） . The infection rate in male （6.67%）is higher than that in female （4.13%）. There was a significant difference. There was no HBsAg positive students who had been vaccinated. Among HBsAg positive students, HBV-DNA positive and HBeAg positive accounted for 53.93% and 51.68% respectively. [Conclusion] After investigation on HBsAg infection and students＇ infected factors,it showed that family HBsAg infection, blood transfusion and use of blood products were the main factors for the students to be infected.