硝苯地平治疗放射性食管炎278例

Nifedipine in treating 278 patients with radio-esophagitis

目的：观察硝苯地平治疗放射性食管炎的疗效。方法：硝苯地平治疗因放射治疗重症肌无力后引起的放射性食管炎２７８例（男性１３５例，女性１４３例，年龄４２±ｓ１０ａ），口服硝苯地平１０ｍｇ，ｔｉｄ，连用２５～３０ｄ。结果：服药ｄ２～５起效，停药后显效２３９例占８６．０％，有效３３例占１１．９％，总有效率为９７．９％，不良反应有轻度头晕和乏力。结论：硝苯地平是治疗放射性食管炎的有效药物。

AIM: To observe the efficacy of nifedipine in treating the radio-esophagitis. METHODS: Two hundred and seventy-eight patients (M 135, F 143, age 42±s 10 a) with myasthenia gravis had radio-esophagitis after radiotherapy, they were treated with nifedipine 10 mg, po, tid for 25-30 d. RESULTS:The results after 2-5d of treatment were:239 patients(86.0%)showed marked improvement,33 patients (11.9%) showed improvement, and the total response rate was 97.9%. Adverse reactions were mild giddiness and weakness. CONCLUSION: Nifedipine is effective in treating radio-esophagitis. 〖KH*2/3D]