海洋来源真菌烟曲霉(Aspergillus fumigatus)次级代谢产物研究(Ⅰ):生物碱

Studies on Chemical Constituents of Secondary Metabolites of Marine-derived Aspergillus Fumigatus(Ⅰ):Alkaloids

对一株海洋来源的微生物中的次级代谢产物进行了研究，从中分离并鉴别了5个喹唑啉生物碱类化合物（1～5），分别为fumiquinazoline G（1），fumiquinazoline F（2），fumiquinazoline A（3），fumiquinazoline C（4）和fumiquinazoline D（5）。

The secondary metabolites of the fermentation of Aspergillus fumigatus were studied. Five alkaloid compounds were isolated by repeated chromatography over silica gel, sephadex LH-20 column and HPLC. Their structures were identified on the basis of comparison to literature and spectroscopic analysis as fumiquinazoline G （1）, fumiquinazoline F （2）, fumiquinazoline A （3）, fumiquinazoline C （4）, and fumiquinazoline D （5）.