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急性发作期哮喘血清与免疫球蛋白的临床意义

Significance of Cytokines and Immunoglobulin in Acute Asthmatic Patients
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摘要 目的:探讨急性发作期哮喘患者血清细胞因子及免疫球蛋白水平的意义。方法:对急性发作期哮喘患者56例及健康人46例进行TNF-α、IL-4、IL-6、IL-8和免疫球蛋白水平测定并作相关性分析。结果:哮喘患者血清TNF-α、IL-4、IL-6、IL-8及IgE、IgG水平明显高于对照组(P<0.05);IgE与TNF-α、IL-4IL-6、IL-8均呈正相关(P<0.01或P<0.001)。结论:TNF-α、IL-4、IL-6、IL-8是参与急性发作期哮喘患者气道炎症的重要细胞因子,针对细胞因子在气道炎症中作用的不同特点采取治疗十分必要。 Objective: To explore the significance of cytokines and in acute asthmatic patients. Methods: Analyzing the correlation of TNF-α.IL-4 .IL-6.IL-8 and immunoglobulin between 56 acute asthmatic patients and 46 health people. Results: The serum level of TNF-α.IL-4.IL-6.IL-8.IgE and IgG in acute asthmatic patients was higher than the health people,P 〈 0.05. The serum level of TNF-α.IL-4.IL-6.IL-8 was positive relative to IgE for acute asthmatic patients. Conclusion: TNF-α.IL-4 .IL-6 and IL-8 were important cytokines in acute asthmatic patients, and according to the different properties of TNF-α.IL-4 .IL-6.IL-8 in respiratory inflammation is necessary.
出处 《岭南急诊医学杂志》 2007年第3期178-179,共2页 Lingnan Journal of Emergency Medicine
关键词 哮喘 细胞因子 免疫球蛋白 asthma cytokines immunoglobulin
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  • 1何权瀛.一氧化氮与支气管哮喘[J].国外医学(呼吸系统分册),1994,14(4):191-194. 被引量:4
  • 2连玉英,王维英,姜秀俐,陶永爱,于秀英,陈颖.支气管肺炎儿血清肿瘤坏死因子-α水平观察[J].实用儿科临床杂志,1996,11(1):19-20. 被引量:6
  • 3冯学斌 刘凤 黄薇 等.白细胞介素8、肿瘤坏死因子及IgG亚类在儿童支气管哮喘发病中的作用研究[J].中国免疫学杂志,1996,12:197-197.
  • 4徐玲玲 华雪玲 陈晓东.儿童哮喘血浆肿瘤坏死因子活性观察[J].中华结核病呼吸杂志,1995,18(3):135-135.
  • 5戴家熊 韩连书.小儿哮喘[M].上海:上海科学技术文献出版社,1997.31-43.
  • 6To Y, Dohi M, Tanaka R et al. Early in interleukin-4 dependent response can induce airway hyperreactivity before development of airway inflammation in a mouse model of asthma. Lab Invest,2001,81 (10) : 1385
  • 7Hughes JM, Rimmer SJ, Salome CM et al. Eosinophilia, interleukin-5, and tumour necrosis factor-alpha in asthmatic children. Allergy, 2001,56(5) :412
  • 8Najam FI, Giasuddin AS, Shembesh AN. Tumour necrosis factors in childhood asthma. Indian J Pediatr,2001,68(3) :217
  • 9戴山林.白介素-10与支气管哮喘[J].国外医学(呼吸系统分册),1997,17(2):57-58. 被引量:10
  • 10薛玉文,李玉.白介素-8与支气管哮喘[J].国外医学(呼吸系统分册),1997,17(2):59-61. 被引量:13

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