血清NAG在肝病诊断中的应用

Application of serum NAG determination in diagnosis of liver diseases

目的:观察血清N-乙酰-β-D氨基葡萄糖苷酶(NAG)活性对临床上几种肝病诊断的价值。方法:用酶法检测50例健康体检者和62例肝病患者(慢性活动性肝炎组,肝硬化组,原发性肝癌组和急性肝炎组)血清中NAG的活性。结果:4组肝病患者血清NAG活性分别为20.7±6.0 V·L-1(P<0.01),22.7±8.7 V·L-1(P<0.01),18.9±6.0 V·L-1(P<0.05),19.3±5.4 V·L-1(P<0.01),均显著高于健康对照组(14.3±2.9)。结论:血清NAG活性测定对临床各种肝病的诊断有价值。

Objective： To observe the value of activity of serum NAG in the clinical diagnosis of several liver diseases. Methods：Determined activity of serum NAG in 50 examples healthy physical examinations and 62 examples liver diseases patients （chronic activity hepatitis group, liver cirrhosis group, primary liver cancer group and acute hepatitis group） with the enzyme law. Results： The activity of serum NAG in 4 groups of liver diseases patients respectively is 20. 7±6.0 V · L^-1 （P（0. 01） ,22. 7±8.7 V · L^-1 （P（0. 01）, 18. 9±6.0 V · L^-1 （P（0.05）, 19.3±5. 4 V · L^-1 （P（0. 01）. Remarkably is higher than the health comparison group（14.3±2. 9）. Conclusion：The activity of serum MAG determination has the value to the clinical each kind of liver diseases diagnosis.