摘要
Objective:To investigate the susceptibility of strains separated from probiotic products for medical purpose to 14 antimicrobial agents.Methods:The single aerobic strains were isolated from these products respectively and disc agar diffusion assay was proceeded to determine the susceptibility.Results: Probiotics tested in the study mostly showed multiresistant to the agents.Lactobacillus acidophilus LAP, LAB,Lactobacillus bulgaricus LBJ and Streptococcus thermophilus STJ were resistant to vancomycin.Con- clusion..Drug resistance exists in most of commercial probiotics.The evaluation and monitoring of safety of probiotic products for medical purpose should be paid great attention.
Objective： To investigate the susceptibility of strains separated from probiotic products for medical purpose to 14 antimicrobial agents. Methods：The single aerobic strains were isolated from these products respectively and disc agar diffusion assay was proceeded to determine the susceptibility. Results： Probiotics tested in the study mostly showed multiresistant to the agents. Lactobacillus acidophilus LAP, LAB, Lactobacillus bulgaricus LBJ and Streptococcus therrnophilus STJ were resistant to vancomycin. Conclusion： Drug resistance exists in most of commercial probiotics. The evaluation and monitoring of safety of probiotic products for medical purpose should be paid great attention.
关键词
中国
药品安全
前生命期
抗菌剂
probiotics
antimicrobial resistan
drug safety
