摘要
Objective:To explore the serum levels of resistin and adiponectin in patients with overweight and obesity.Methods:Fifty-eight cases with normal weight and 24 patients with overweight and obesity have taken fasting blood samples for measurements of plasma glucose,plasma lipids,insulin,C-peptide, thyroid hormones,C-response protein,interleukin-6,TNF-α,leptin,adiponectin and resistin.Results: The concentrations of resistin in cases with overweight and obesity were significant higher than those in the normal weight cases (16.01±8.60 vs 11.63±9.05ng/ml,P=0.047).Pearson relation analysis showed that serum resistin concentrations were positively correlated with age (r=0.476,P=0.019),but negatively correlated with C-peptide (r=-0.45,P=0.024),and adiponectin concentrations were posi- tively correlated with HDL-c (r=0.463,P=0.023) and systolic blood pressure (r=0.409,P=0.047)in overweight and obesity cases.Conclusion:The concentrations of resistin in cases with over-weight and obesity are higher,and there is no correlation between resistin and blood glucose,blood lipids and insulin, while the serum adiponectin concentrations positively correlated with HDL-c and systolic blood pressure.
Objective： To explore the serum levels of resistin and adiponectin in patients with overweight and obesity. Methods： Fifty-eight cases with normal weight and 24 patients with overweight and obesity have taken fasting blood samples for measurements of plasma glucose, plasma lipids, insulin, C-peptide, thyroid hormones, C-response protein, interleukin-6, TNF-α, leptin, adiponectin and resistin. Results： The concentrations of resistin in cases with overweight and obesity were significant higher than those in the normal weight cases （16. 01 ± 8. 60 vs 11. 63 ± 9. 05 ng/ml, P = 0. 047）. Pearson relation analysis showed that serum resistin concentrations were positively correlated with age （r= 0. 476, P = 0.019）, but negatively correlated with C-peptide （r=-0.45, P=0. 024）, and adiponectin concentrations were positively correlated with HDL-c （r=0. 463, P=0. 023） and systolic blood pressure （r=0. 409, P=0. 047） in overweight and obesity cases. Conclusion： The concentrations of resistin in cases with over-weight and obesity are higher, and there is no correlation between resistin and blood glucose, blood lipids and insulin, while the serum adiponectin concentrations positively correlated with HDL-c and systolic blood pressure.
