摘要
建立体外溶出度检查方法，使之能控制控释或缓释制剂的质量并能检出批间是否生物等效，最好是在体内释放曲线的基础上寻找具有与其相关性最好的体外溶出曲线的检查方法。
To establish a good dissolution in vitro that can effectively control the quality of controlled/sustained release dosage forms and show if they are bioequivalent betwean batches ,the best method is to find out the dissolution curve which is significant correlation with the release curve on the basis of the in vivo release kinetics .
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
1997年第1期43-47,共5页
Chinese Journal of Pharmaceuticals
关键词
体外溶出曲线
体内释放曲线
溶出度
缓释制剂
dissolution in vivo, release kinetics, controlled/modified release dosage forms
