摘要
多发性骨髓瘤(MM)是浆细胞克隆增生性恶性肿瘤,其治疗效果较差,迄今仍视为不可治愈的疾病。近年来着眼于MM细胞内信号通路、骨髓微环境及二者的相互作用,MM的治疗有了很大进展。该文综述了MM的化学治疗、造血干细胞移植、生物治疗、支持治疗及免疫治疗现状及其进展。
Multiple myeloma(MM) is a kind of malignancy with plasmocyte's clonal hyperplasia, which have a poor therapeutic reaction, and has been regarded as an incurable malignancy . in recent years, therapy of MM gains great development because of the research to intra - cellular signal passageway, marrow microenvironment and their interaction. This article reviews current situation and recent advances about chemotherapy, hemopoietic stem cell transplant, biotherapy, supportive treatment and immunotherapy of MM.
出处
《现代肿瘤医学》
CAS
2007年第7期1013-1016,共4页
Journal of Modern Oncology