摘要
目的观察益肾颗粒剂对狼疮性肾炎患者的sFas/sFasL及临床相关生化指标的影响。方法将60例狼疮性肾炎患者随机分为治疗组(益肾颗粒剂组)和对照组(强的松组),对比服药8周前后两组患者的sFas/sFasL及其24 h尿蛋白定量、血清尿素氮、肌酐的变化。结果两组患者治疗后sFas/sFasL及其24 h尿蛋白定量、血清尿素氮、肌酐等指标均有明显改善(P<0.05),但两组患者治疗后各指标比较差异无统计学意义(P>0.05)。结论益肾颗粒剂对狼疮性肾炎有良好的治疗作用。
Objective To observe the effect of Yishen granule on sFas/sFasL and clinical biochemistry in patients with lupus nephritis（LN）. Methods 60 patients with LN were randomly divided into treatment group（n=30） and control group（n=30）; and sFas/sFasL was campared with urinary protein excretion, 24 hours blood serum creatinine （Scr） and blood urea nitrogen（BUN） between treatment group and control group after 8 weeks taking Yishen granule and prednison. Results The differenc compared sFas/sFasL with 24 hours urinary protein excretion, Scr, BUN in the two groups, are significantly （P〈0.05）, however, which are not significant difference （P〉 0.05） after treating. Condution Yishen granule is effective to treatment of LN.
出处
《湖南中医药大学学报》
CAS
2007年第3期37-39,共3页
Journal of Hunan University of Chinese Medicine
基金
国家中医药管理局基金项目(02-03.LLII)
