期刊文献+

基于自适应免疫遗传算法的多序列比对 被引量:4

Multiple sequence alignment based on immune adaptive genetic algorithm
下载PDF
导出
摘要 针对多序列比对问题提出一种基于自适应免疫遗传算法的多序列比对方法。为了保持群体中个体的多样性,以及加快算法的收敛速度,该算法中交叉概率和变异概率根据群体的多样性自适应调整,并且在选择免疫算子时采用择优策略,将免疫算子引入到自适应遗传算法中,通过对个体接种疫苗来进一步提升个体的存活能力。 In this paper, an immune adaptive genetic algorithm is presented to solve multiple sequence alignment. In order to maintain diversity of individual in' population and expedite convergence speed of the algorithm, this method changes crossover probability and mutation probability based on variety of population. Besides it adopts superior strategy as selecting immtme operator, that it is introduced into adaptive genetic algorithm, which accelerates performance of individual
出处 《信息技术》 2007年第2期15-17,111,共4页 Information Technology
基金 国家自然科学基金(90304010)
关键词 生物信息学 多序列比对 免疫遗传算法 算子 bioinformatics multiple sequence alignment immune genetic algorithm operator
  • 相关文献

参考文献5

  • 1李素贞,莫忠息,张轩,陶玉敏.基于免疫遗传算法的多重序列比对[J].武汉大学学报(理学版),2004,50(5):537-541. 被引量:4
  • 2梁俊明,刘芳.混合遗传算法及其实现研究[D].
  • 3Klaus Bucka-Lassen,Ole Caprani,Jotun Hein.Combining many multiple alignments in one improved alignment[J].1999,11:122-130.
  • 4Cédric Notredame,Desmond G Higgins.SAGA:sequence alignment by genetic algorithm[J].Nucleic Acids Research.
  • 5Stefan Schroedl.An Improved Search Algorithm for Optimal Multiple-Sequence Alignment[J].Journal of Artificial Intelligence Research.2005,5:587-623.

二级参考文献11

  • 1Shi Feng, Huang Jing, Mo Zhong-xi, Zheng Hui-rao School of Mathematics and Statistics, Wuhan University, Wuhan 430072, Hubei, China.A Genetic Algorithm on Multiple Sequences Alignment Problems in Biology[J].Wuhan University Journal of Natural Sciences,2002,7(2):139-144. 被引量:3
  • 2Wang L, Jiang T. On Complexity of Multiple Sequence Alignment[J]. J of Comput Biol,1994,1(4):337-348.
  • 3Notredame C. Recent Progresses in Multiple Sequence Alignment: A Survey[J]. Pharmacogenomics, 2002,3(1):131-144.
  • 4Thompson J D,Higgins D G,Gibson.CLUSTAL W:Improving the Sensitivity of Progressive Multiple Alignment Through Sequence Weighting,Positions-specific Gap Penalities and Weight Matrix Choice[J].Nacleic Acids Research,1994,22:4673-4680.
  • 5Notredame C, Higgings D C. SAGA: Sequence Alignment by Genetic Algorithm[J]. Nucleic Acids Res,1996,24(8):1515-1524.
  • 6Zhang C, Wong A K. A Genetic Algorithm for Multiple Molecular Sequence Alignment[J]. Comput Appl Biosci,1997,13(6): 565-581.
  • 7Joao Setubal, Joao Meidanis. Introduction to Computational Molecular Biology[M]. Brazil: Brooks/Cole Publishing Company, 1997. 70-71.
  • 8Just W.Computation Complexity of Multiple Alignment with SP-score[J].J of Comp Biol,2001,8(6):615-623.
  • 9Chun J S, Jung H K, Hahn S Y. A Study on Comparison of Optimization Performances between Immune Algorithms and Other Heuristic Algorithms[J]. IEEE Transaction on Magnetics,1998,34(5):2972-2975.
  • 10王磊,潘进,焦李成.免疫算法[J].电子学报,2000,28(7):74-78. 被引量:351

共引文献3

同被引文献27

引证文献4

二级引证文献18

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部