中药盐炙共性技术研究思路探析

Discussion of Research Method of Common Technique of Stir-heating with Salt-solution of TCM

目的探讨中药盐炙共性技术研究的思路,为临床提供质量稳定、可控,疗效可靠,使用安全的中药饮片。方法在文献研究、专家咨询、实验预试、结果分析的基础上,逐步完善实验方案,形成了中药盐炙共性技术研究新思路。结果首次提出采用"文献研究-中药炮制-辅料检测-药性理论-化学成分-药理作用-谱效关系-药物代谢-方剂疗效"的综合研究模式。结论利用该研究模式,能够通过对盐炙共性技术进行多指标、综合评价、系统分析来阐明中药盐炙的科学内涵,为临床用药提供理论依据,为中药炮制提供一种新的研究模式和思路。

Objective To investigate common technique of stir- heating with salt- solution of TCM, and to provide safe cut crude drug with stable and under- controlled quality, reliable curative effect for clinical use. Methods Based on document researching, expert consultation, pre- experiment and result analysis, we consummated the schedule of experiment and formed new idea of research of common technique of stir- heating with salt- solution of TCM, Results Firstly introduced the combinative research mode of ＂document researching- processing of TCM-detection of adjuvant-theory of drug property- chemical composition- pharmacological action- relationship of colour spectrum and effect- drug metabolism- curative effect of prescription＂. Conclusion We expect to do some systematic analysis by multicriteria combinative evaluation, elucidate the scientific connotation of stir- heating with salt- solution, and provide the theory for clinical use and a new research mode of processing of TCM.