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脑胶质瘤术后^(125)I粒子永久植入近距离内放疗的临床应用与观察 被引量：3

Clinical study of brachytherapy with Iodine-125 for gliomas
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摘要 目的探讨配合手术治疗进行125I粒子永久植入近距离放疗治疗脑胶质瘤的临床疗效及操作方法。方法11例脑胶质瘤患者在手术治疗同时结合CT、术中及直视下进行125I粒子植入治疗,肿瘤匹配剂量90～110Gy,每颗粒子剂量0.7mCi,每例患者植入粒子数8～10颗。结果随访一年,死亡2例,存活9例,9例患者卡氏评分较治疗前有提高,随访期内,无严重并发症。结论此技术适应证广,安全有效,为恶性脑胶质瘤的综合治疗增添了新的手段。 Objective To study the clinical efficacy of brachytherapy with Iodine-125 for gliomas. Methods From October 2005 to October 2006,11 patients were treated by the implantation of ^125I radionuclide. Results Over one year survival in 9 cases, no acute or chronic radiation side effect were observed in the follow-up. Conclusions The implanting of ^125I radionuclide can evidently improve the quality of life and prolong survival time. It is an effective method for the treatment of gliomas.
作者 马骏 耿晓增 程刚 陈海峰 傅震
机构地区 南京医科大学 南京医科大学第一附属医院神经外科
出处 《临床神经外科杂志》 CAS 2007年第2期55-57,共3页 Journal of Clinical Neurosurgery
关键词 脑胶质瘤 近距离疗法 ^125I放射性粒子 glioma iiradiation therapy brachytherapy Iodine-125
分类号 R730.264 [医药卫生—肿瘤]
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共引文献11

同被引文献17

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引证文献3

二级引证文献15

临床神经外科杂志
2007年 第2期

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