摘要
以叔丁基肼盐酸盐为起始原料,与对乙基苯甲酰氯反应合成N-(4-乙基苯甲酰基)-N'-叔丁基肼,反应收率97.9%。其再与3,5-二甲基苯甲酰氯反应合成虫酰肼,纯度大于96%,总收率大于86%。
N-（d-Ethylbenzoyl）-N＇-t-butylhydrazine was prepared from tert-butyl hydrazine hydrochloride and pethylbenzoyl chloride, the yield of the product reached 97.9%. After that, reaction of N-（4-ethylbenzoyl）-N＇-t- butylhydrazine with 3,5-dimethylbenzoyl chloride to give target product tebufenozide. The purity and total yield of the product was more than 96% and 86%, respectively.
出处
《精细化工中间体》
CAS
2007年第3期32-34,共3页
Fine Chemical Intermediates
关键词
叔丁基肼盐酸盐
对乙基苯甲酰氯
3
5-二甲基苯甲酰氯
虫酰肼
合成
tert -butylhydrazine hydrochloride
p -ethylbenzoyl chloride
3,5 -dimethyl benzoyl chloride
tebufenozide
synthesis
