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冠心病合并2型糖尿病患者血清白介素-18水平检测 被引量:2

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摘要 目的:观察冠心病合并2型糖尿病患者血清白介素-18(IL-18)水平及其临床意义。方法:冠心病患者127例,根据是否合并2型糖尿病分为伴2型糖尿病组(42例)和不伴糖尿病组(85例),与正常对照组55例比较,采用双抗体夹心ELISA法测定血清IL-18。结果:伴2型糖尿病组和不伴糖尿病组年龄、体重指数(BMI)及血脂差异均无统计学意义(P〉0.05);冠心病患者血清IL-18水平明显高于正常对照组(P〈0.01);与不伴糖尿病组相比,伴2型糖尿病组血清IL-18水平明显升高(P〈0.01)。结论:合并2型糖尿病的冠心病患者血清IL-18水平高,可能是其易发生致死性心血管事件的重要原因,对这类人群需积极采取措施进行二级预防。
出处 《中国医师杂志》 CAS 2007年第6期834-835,共2页 Journal of Chinese Physician
基金 湖北省卫生厅2005-2006年度资助重点项目(项目编号:JXZA29)
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共引文献7

同被引文献18

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