小儿急性肾功能衰竭46例临床分析

Clinical analysis of childhood acute renal failure

目的比较小儿单纯急性肾功能衰竭与合并多脏器功能衰竭的临床特点及治疗转归。方法回顾性分析46例急性肾功能衰竭患儿的临床资料。结果急性肾功能衰竭合并多脏器功能衰竭的患儿病死率明显高于单纯急性肾功能衰竭。结论对急性肾功能衰竭合并多脏器功能衰竭的患儿宜早诊断,早治疗,及时处理原发病,消除病因,改善代谢,纠正组织缺氧,全面有效的脏器支持,维护脏器功能,是治疗成功的关键。

Objective To investigate the clinical features and treatment outcomes of acute renal failure and multiple system organ failure in children. Methods Clinical data of 46 pediatric acute renal failures admitted into our hospital from 1994 to 2005 were retrospectively analysed. Results The death rate was obviously higher in patients implicating in acute renal failure concurrent multiple system organ failure than those suffering acute renal failure only. Conclusion Early diagnosis and treatment, especially the management to primary diseases, improving metabolism and rectifying hypoxia, and overall organ support are all essential to the success of the treatment.