摘要
1,2,4-三甲氧基苯经付-克酰化得1-(2,4,5-三甲氧基苯基)丙酮,再经还原羰基和脱水反应得α-细辛脑,总收率61%。
α-Asarone was synthesized from 1,2,4-trimethoxybenzene via Friedel-Crafts reaction to give 1- (2,4,5-trimethoxyphenyl) propanone, which was subjected to reduction and then dehydration with an overall yield of 61%.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
2007年第7期477-478,共2页
Chinese Journal of Pharmaceuticals