摘要
目的观察丙泊酚、氨胺酮、利多卡因(PKL)合剂用于肠镜检查的临床效果。方法70例需行肠镜检查的患者分为两组,P组丙泊酚用量为3 mg/kg;PKL组以丙泊酚用量计算,为0．6 mg/kg。比较两组的镇痛效果、丙泊酚的用量、对呼吸及循环的影响和苏醒时间的差异。结果PKL组镇痛效果强于P组,差异有统计学意义(P<0．05);PKL组的丙泊酚用量明显少于P组(P<0．05),且苏醒时间明显短于P组(P<0．05);PKL组的BP、HR与P组相比差异有统计学意义(P<0．05),诱导5 min内SpO2降低较P组明显(P<0．05)。结论PKL用于肠镜检查,镇静镇痛效果好,丙泊酚的用量明显减少,苏醒时间缩短,对循环有支持作用。
Objective To observe the clinical effect of intravenous propofol, ketamine and lidocaine mixture （PKL） on enteroscopy. Methods Seventy cases undergoing enteroscopy were divided into two groups, P group and PKL group. The propofol dose in P group and PKL group was 3 mg/kg, and 0.6 mg/kg respectively. The analgesic effects,the dose of propofol ,the effect on respiration and circulation, and the time of palinestbesia in the two groups were compared. Results The analgesic effect in the PKL group was significantly better than that in P group（ P 〈0.05 ）. Propofol dose was significantly lower than that in P group （ P 〈0.05 ）, and the time of palinestbesia was significantly shorter than that in P group （ P 〈0.05 ）. BP and HR were more stable but SpO2 was lower within 5 rain during induction in PKL group compared with P group （ P 〈0.05 ）. Conclusion Using PKL in enteroscopy has several advantages, such as better analgesic effect,lower dose of propofol, shorter time of palinesthesia and supporting effect to circulation.
出处
《实用疼痛学杂志》
2007年第3期201-203,共3页
Pain Clinic Journal
