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原发性胆汁性肝硬化基因易感性的研究进展 被引量：5

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作者 吴传勇 邓安梅 仲人前
机构地区 第二军医大学长征医院实验诊断科全军临床免疫中心
出处 《肝脏》 2007年第3期207-209,共3页 Chinese Hepatology
基金 国家自然科学基金(30471616) 上海市重大科技攻关基金(04DZ19116) 上海市重点科研支撑条件项目(051409012) 上海市重点基础研究项目(05JC14052) 上海市青年科技启明星计划(QMX01423)资助
关键词 原发性胆汁性肝硬化 基因易感性 易感性相关基因 自身免疫机制 抗线粒体抗体 非化脓性炎症 年发病率 胆汁淤积性
分类号 R575.2 [医药卫生—消化系统]
  • 相关文献

参考文献10

  • 1Fan LY,Zhong RQ,Kong XT,et al.Study on the relationship of CTLA-4-318,+ 49 polymorphisms with autoimmune hepatitis and primary biliary cirrhosis in a Chinese population.Zhonghua Yi Xue Yi Chuan Xue Za Zhi,2004,21:440-443.
  • 2Daimon Y,Yamanishi K,Murakami Y,et al.Novel single nucleotide polymorphisms of the cytokeratin 19 pseudogene are associated with primary biliary cirrhosis.Hepatol Res,2003,25:281-286.
  • 3Matsushita M,Miyakawa H,Tanaka A,et al.Single nucleotlde polymorphisms of the mannose-binding lectin are associated with susceptibility to primary biliary cirrhosis.J Autoimmun,2001,17:251-257.
  • 4Donaldson P,Agarwal K,Craggs A,et al.HLA and interleukin 1 gene polymorphisms in primary biliary cirrhosis:association with disease progression and disease susceptibility.Gut,2001,48:397-402.
  • 5Selmi C,Zuin M,Biondi ML,et al.Genetic variants of endothelial nitric oxide synthase in patients with primary biliary cirrhosis:association with disease severity.J Gastroenterol Hepatol,2003,18:1150-1155.
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  • 7Bittencourt PL,Palacios SA,Farias AQ,et al.Analysis of major histocompatibility complex and CTLA-4 alleles in Brizulian patients with primary biliary cirrhosis.J Gastroenterol Hepatol,2003,18:1061-1066.
  • 8Invernizzi P,Battezzati PM,Crosignani A,et al.Peciliar HLA polymorphisms in Italian patients with primary biliary cirrhosis.J Hepatol,2003,38:401-406.
  • 9Matsushita M,Tanaka A,Kikuchi K,et al.Association of single nucleotide polymorphisms of the interleukin-10 promoter gene and susceptibility to primary biliary cirrhosis:immunogenetic differences in Italian and Japanese patients.Autoimmunity,2002,35:531-536.
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同被引文献54

  • 1李蕴铷.自身免疫性肝病的诊断和治疗[J].继续医学教育,2006,20(7):52-55. 被引量：3
  • 2Liver Disease Committee,Chinese Association of Integrative Medicine..肝纤维化中西医结合诊疗指南[J].中华肝脏病杂志,2006,14(11):866-870. 被引量：270
  • 3叶维法 主编.临床肝胆病学[M].天津：天津科学技术出版社,1983.942-945.
  • 4Jorge D. Ursodeoxy cholic acid inhibits induction of the human intestinal epithelial nitric oxide synthase [ J ]. Hepatology, 1995,22 ( 4 ) : 361.
  • 5Prince M, Chetwynd A, Newman W, et al. survid and sympton Progerssion in a geographically based cohort of patients with primary biliary cirrhosis: follow - up for up to 28 years [ J]. Castroenterology, 2002,123(4) : 1044 - 1051.
  • 6Dickson ER, Grambasch PM, Fleming TR,et al. Prognosis in Primary biliary cirrhosis: model for decision making [ J ]. Hepatoiogy, 1989, 10(1):1-7.
  • 7Heathcote EJ. Management of primary biliary cirrhosis. The AmeriAssociation for the study of Liver Diseases practice guidelines [ J ]. Hepatology,2000,31 ( 4 ) : 1005 - 1013.
  • 8Lazaridis KN, Gores G J, Lindor KD. Uresodeoxy cholic acid mechamism of action and clinical use in hepatobiliary disorders[ J]. Hepatol, 2001,35: 134 - 146.
  • 9Paumgartner G, Beucerss U. Ursodoxy cholic acid in cholestatic liver disease:mechanism of acion and therapeutic use revisited[ J]. Hepatology,2002,36: 525 - 531.
  • 10Pares A, Caballeria L, Rodes J, et al. Long - term effects of ursodeoxycholic acid in primary biliary cirrhosis:results of a double - blind controlled multicen tric trial[ J]. Hepatol,2000,32:561 - 566.

引证文献5

二级引证文献31

肝脏
2007年 第3期

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