大花翠雀化学成分的研究

Study on the chemical constituents of Delphinium grandiflorum L.

采用常压柱层析及薄层层析从大花翠雀(Delphinium grandiflorum L.)中分离出7个化合物,利用物化特性及波谱分析鉴定了其中6个化合物的结构,分别为4′,7-二甲氧基-5-羟基黄酮(1),1-O-去甲基塔拉萨敏(2),甲基牛扁亭(3),翠雀胺(4),翠雀固灵(5),大花翠雀素(6).经文献检索确定化合物1,2均系首次从该植物中分离得到.

Seven constituents are isolated from Delphinium grandiflorum L. by column chromatography and thin layer chromatography. The structures of six constituents are determined on the basis of their physicochemical characters and spectrum evidence as follows： 4＇, 7- dimethoxy- 5- hydroxyflavone （ 1 ）, isotalatizidine（2）, methyllycaconitine（3）, delcosine（4）, delsoline（5）, grandiflorine（6）. Compounds 1 and 2 are obtained from this plant for the first time.