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结核性脑膜炎脑脊液中粒细胞集落刺激因子的测定 被引量:8

Measurement of Granlocytes Colony-Stimulating Factor (G-CSF) in Cerebrospinal Fluid (CSF) from patients with Tuberculous Meningitis
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摘要 本文采用ELISA法检测23例结核性脑膜炎及21例非结核性脑膜炎脑脊液中的G-CSF。结脑组(0.65+0.32OD)明显高于非结脑组(0.15±0.11OD)(P<0.01)。诊断结脑的敏感性为91.3%,特异性为90.5%。G-CSF在抗感染的非特异性细胞免疫中起重要作用,细菌及其产物是刺激和调节G-CSF产生的主要物质。 G-CSF was measured in 23 cases of tuherculous meningitis and 21 cases of nontuberculous meningitis using ELISA method. The G-CSF levels of CSF in group of tuherculuus meningitis (0. 65±0. 32OD) were significantly higher than group of nontu- berculous meningitis (0. 15±0.11OD) (P<0. 01). Their positive rates were shown to be 91. 3% and 90. 5% respectively. The differ- ence between the two groups was statistically singnificant ( P<0. 01). The sensitiviity, specificity and accuracy were 91. 3%, 90. 5% and 90. 9% respectively for diagnosis of tuberculous meningitis.
出处 《中国防痨杂志》 CAS 1997年第1期29-30,共2页 Chinese Journal of Antituberculosis
关键词 结核性脑膜炎 脑脊液 G-CSF 测定 Granlocytes colony-stimulating factor Tuberculosis Meningeal Cerebrospinal fluid
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