摘要
1例76岁糖尿病女性患者,口服二甲双胍10年后,加用瑞格列奈1mg,2次/d治疗,后又加服罗格列酮4mg,1次/d,5个月后出现出汗、乏力、气短、面色苍白等症状。实验室检查:Hb84g/L,RBC2.87×1012/L,HCT0.26。停用罗格列酮并对症治疗,1个半月后血红蛋白上升至110g/L,红细胞及红细胞压积正常。
A 76-year-old woman with diabetes mellitus received oral dimethylbiguanide for 10 years. Repaglinide ling twice daily and then rosiglitazone 4mg once daily were added to her regimen. Five months later, she developed sweat, weakness, short of breath, pale face, and so on. Laboratory tests revealed the following values： Hb 84 g/L, RBC 2.87× 10^12/L, HCT 0.26. She discontinued rosiglitazone and received symptomatic therapy. One month and a half later, the level of Hb was increased to 110 g/L, RBC and HCT were normal.
出处
《药物不良反应杂志》
2007年第3期206-206,共1页
Adverse Drug Reactions Journal
关键词
罗格列酮
二甲双胍
贫血
rosiglitazone
dimethylbiguanide
anaemia
