摘要
1名57岁女性右侧丘脑出血患者,因肌痉挛用巴氯芬5～15mg,3次/d治疗。3个月后,停用巴氯芬改用盐酸替扎尼定1mg,3次/d。服药后第2天,患者出现兴奋、欣快,思维紊乱,言语杂乱。血、尿、便常规,电解质、肝、肾功能等检查正常,头颅CT未见新发病灶,内科及神经系统查体无新发体征。停用替扎尼定后,患者情绪逐渐稳定,未再出现类似精神症状。
A 57-year-old woman with right thalamic hemorrhage was administered with baclofen 5-15mg thrice daily for treating his myospasm. Three months later, her regimen was changed to tizanidine hydrochloride lmg thrice daily. On day 2 after administration of tizanidine, she developed excitement, euphoria, disturbance of thinking, and incoherence of speech. The values of laboratory tests revealed that the blood, stool, urine, electrolytes, liver and renal function were normal. A head CT scan showed no new focus was found. A medical and neurological examination revealed there was no new physical sign. After stopping use of tizanidine, the patient＇s emotion was stabilized gradually and other similar psychiatric symptoms did not reappear.
出处
《药物不良反应杂志》
2007年第3期207-207,共1页
Adverse Drug Reactions Journal
关键词
盐酸替扎尼定
精神症状
tizanidine hydrochloride
psychiatric symptom
