碘普罗胺注射液300引起严重过敏反应

Severe allergy due to iopromide injection 300

肝功能异常女性患者,56岁,于肝脏CT增强扫描前静脉注射地塞米松10mg、碘普罗胺注射液30050ml。10min后,出现面色潮红、胸闷、气促,随后昏迷。立即给予吸氧、静脉滴注地塞米松10mg、肌内注射异丙嗪25mg,患者BP155/75mmHg,心电图示窦性心动过速,急查血糖14.5mmol/L、WBC13.74×109/L、血钾2.0mmol/L。经输液、补充电解质、抗过敏治疗后,患者恢复神志。

A 56-year-old woman with liver dysfunction was administered with IV dexamethasone 10mg, and then IV iopromide 300 50ml before liver enhanced CT scan. Ten minutes later, she developed facial flushing, chest distress, tachypnea, and coma. Immediately, she was treated with oxygen, IV dexamethasone 10mg, IM proazamine 25mg. Her BP was 155/75mmHg. An electrocardiogram showed sinus tachycardia. Laboratory tests revealed the following levels： Glu 14.5mmol/L, WBC 13.74×10^9/L, and potassium 2.0 mmol/L. After treatment with fluid replacement, electrolyte supplement, and anti-allergy agent, the patient＇s consciousness was restored.