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选择性5-羟色胺再摄取抑制剂应用与评价 被引量:14

Evaluation and Application of the Selective Serotonin Reuptake Inhibitor
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摘要 目的:抑郁症是神经内科的常见和多发病,伴随着对抑郁发病机制的解译,治疗新药不断问世,本文介绍选择性5-羟色胺再摄取抑制剂进展和临床应用的侧面。方法:采用国内、外文献综述方法。结果及结论:作为抗抑郁药中的一支奇葩,选择性5-羟色胺再摄取抑制剂进展迅猛,对5-HT受体有高度的选择性,标志一个新的里程的开始,从而在解除抑郁症上展现了良好的治疗前景。 OBJECTIVE : Depressive disorder is a common and frequently encountered disease in department of neurology with the understanding of its pathogenesis and the appearing of new antidepressant drugs. The objective of our study is to introduce the progress and clinical application of selective serotonin reuptake inhibitor. METHODS: The analysis was performed by reviewing literature both at home and abroad. RESULTS & CONCLUSION: As a new antidepressant drug, selective serotonin reuptake inhibitor experienced a rapid progress ; and the finding that selective serovtonin reuptake inhibitor is highly selective to 5 - HT receptors was a milestone in medicine since it showed a satisfactory prospect for the, relieving of depressive orders.
作者 张石革
出处 《中国医院用药评价与分析》 2007年第3期172-175,共4页 Evaluation and Analysis of Drug-use in Hospitals of China
关键词 抑郁症 选择性5-羟色胺再摄取抑制剂 单胺氧化酶抑制剂 三环类抑郁药 选择性去甲肾上腺素再摄取抑制荆 5-羟色胺受体拮抗剂/再摄取抑制剂 Depressive disorder Selective Serotonin Reuptake Inhibitor (SSRI) Monoamine Oxidase Inhibitor(MAOI) Tricyclic antidepressants ( TCAs ) Selective Noradrenalin Reuptake Inhibitor ( NARI ) Serotonin Receptor Antagonist/Reuptake Inhibitor
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