期刊文献+

外科手术预防应用抗菌药物情况调查与分析 被引量:14

Preventive Use of Antibacterials in Surgery:Survey and Analysis
下载PDF
导出
摘要 目的:了解外科手术预防性应用抗菌药物的情况。方法:回顾性调查2006年4月-6月Ⅰ、Ⅱ类切口手术病历202份,填写调查表进行统计分析。结果:预防性抗菌药物使用率100%;使用频率最高的药物是3代头孢菌素加β内酰胺酶抑制剂;联合用药63.37%;疗程最短2天,最长20天,平均5.88天;术前30分钟用药15.35%。结论:本次调查显示,外科预防用抗菌药物在用药指征、药物选择、用药时机、使用疗程等方面存在诸多问题,应引起足够的重视。 OBJECTIVE: To investigate the preventive use of antibacterials in surgery. METHODS: 202 operation histories of type I and II incisions from April to June of 2006 were reviewed retrospectively and analyzed statistically by questionnaire survey. RESULTS: 100% had preventive use of antibacterials. Leading the first in terms of DDDs was third generation cephalosporin and enzyme inhibitors; 63.37 % had combined use of drugs; the course of treatment ranged from 2 to 2 days, with an average of 5.88 days; 15.35% used drugs 30 min before surgery. CONCLUSION: The survey showed that there are still many problems involved in the preventive use of antibacterials in surgery, e.g. medication indications, choice of drugs, medication time, course of treatment etc, all of which call for our attention.
作者 罗红
出处 《中国医院用药评价与分析》 2007年第3期205-206,共2页 Evaluation and Analysis of Drug-use in Hospitals of China
关键词 外科手术 预防用抗菌药物 调查 Surgery Preventive antibacterials Survey
  • 相关文献

参考文献6

二级参考文献32

  • 1殷凯生 殷民生.实用抗感染药物手册[M].北京:人民卫生出版社,2002.616.
  • 2Pea F,Viale P,Furlanut MI. Antimicrobial agents in elective surgery:prophylaxis or " early therapy" ? [ J ]. J Chemother,2003,15 ( 1 ) : 3 -11.
  • 3Geroulanos S,Marathias K, Kriaras J ,et cd. Cephalosporins in surgical prophylaxis[J]. J Chemother,2001,13sec( 1 ) :23-26.
  • 4Fry DE. Basic aspects of and general problems in surgical infection [J]. Surg Infection(Larchmt) ,2001,2 Suppl( 1 ) :S3-11.
  • 5DiPiro JT. Short-term prophylaxis in clean-contaminated surgery [ J]. J Chemother, 1999,11 (6) :551-555.
  • 6Kriaras I ,Michalopoulos A ,Turina M ,et al. Evolution of antimicrobial prophylaxis in cardiovascular surgery[J]. Eur J Cardiothorac Surg, 2000,18(4) :440-446.
  • 7Classen DC ,Evans RS,Pestotnik SL,et al. The riming of prophylactic administration of antibiotics and the risk of surgical-wound infection [ J ]. N Engl J Med, 1992,326 ( 5 ) :281-286.
  • 8Zanetti G,Giardina R, Platt R. lntraoperative redosing of cefazolin and risk for surgical site infection in cardiac surgery[ J]. Emerg Infection Dis,2001,7(5 ) :828-831.
  • 9Bucknell SJ, Mohajeri M, Low J, et al. Single-versus multiple-dose antibiotics prophylaxis for cardiac surgery [ J ]. Aust N Z J Surg ,2000,70 ( 6 ) :409 -411.
  • 10Carrel T,Eisinger E,Vogt M ,et al. Pneumonia after cardiac surgery is predictable by tracheal aspirates but can not be prevented by prolonged antibiotic prophylaxis[ J]. Ann Thorac Surg,2001,72( 1 ) : 143-148.

共引文献235

同被引文献64

引证文献14

二级引证文献64

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部