利用PASS系统对我院住院医嘱调查分析

Analysis of Inpatient Medical Orders in Our Hospital Using Prescription Automatic Screening System(PASS)

目的：了解住院患者的合理用药情况。方法：应用PASS软件进行相互作用分析，“医院患者信息查询系统”查询病历。结果：调查涉及814例患者29156条住院医嘱，涉及药物526种，出现频率依次为水、电解质平衡调节类、抗感染药、维生素和矿物质、抗肿瘤药、消化系统用药等；当用药品种为1种．4种、5种～10种、〉10种时，存在药物不良相互作用的比例分别为6.49％、25％、49．76％。结论：为防止发生药物相互作用，临床应注意合理用药，尽量减少用药品种，避免不合理用药。

OBJECTIVE： To investigate the rationality of drug use in inpatients. METHODS： Prescription Automatic Screening System （PASS） was used for the analysis of interaction, and the Hospital Patients Information Inquiry System was used for the inquiring of case histories. RESULTS： 29 156 prescriptions of 814 inpatients were surveyed. A total of 526 drugs were involved. The leading drug kinds in terms of frequency of occurrence in descending order were as follows ： drugs regulating water and electrolytes, antimicrobials, vitamins and minerals, antineoplastic agent and gastro-intestinal drugs etc. The incidences of adverse reactions for combined use of 1 - 4, 5 - 9 and over 10 kinds of drugs were 6.49%, 25% and 49.76 % respectively. CONCLUSION： In order to avoid adverse reactions, the use of drugs should be rational and the drug use kinds should be reduced as far as possible to avoid irrational drug use.