急性重症支气管哮喘并呼吸衰竭无创通气的治疗研究

Clinical Study Of Noninvasive Ventilation On Acute And Severe Bronchial Asthma With Respiratory Failure

目的探讨无创正压通气对急性重症支气管哮喘并呼吸衰竭患者的治疗价值。方法38例随机分为两组治疗组20例对照组18例,治疗组在常规治疗基础上加用双水平正压通气,对照组仅给予常规治疗。结果治疗3 d后两组患者的呼吸频率(RR)、心率(HR)、动脉血PH、PaO2、PaCO2、SaO2均较前有明显的改善(P<0.01)。与对照组比较,治疗组在治疗12h,3 d后PH,PaO2,SaO2,PaCO2的改善优于对照组(P<0.01),缓解时间明显缩短(P<0.01),住院时间缩短更明显(P<0.01),但两组患者插管率无明显差异(P>0.05)。结论在常规治疗基础上同时加用双水平正压通气可有效改善患者的治疗效果。

Objective To evaluate the value of Noninvasive Ventilation On Acute And Severe Bronchial Asthma With Respiratory Failure. Methods Thirty-eight patients were randomly into two group ; The therapy group receive BiPAP ventilation on the base of routing h, eatment,the control group only receive routing treatment. Results Two group patients HR,RR,PH,PaO2 ,PaCO2 ,SaO2 were improved after 3 d＇treatment, but Improvement in PH, PaO2 , PaCO2 , SaO2 in therapy group were rapid and significant compare the control group at 12 h. 72 b （P 〈 0. 01 ）, Alleviate time were obviously shortening, The therapy group also lowered the lenth of hospital stay （P 〈 0. 01 ）, but Rate of endotrecheal intubation is no significant difference（ P 〉 0.05）. Condusion Using noninvasive ventilation base on routing treatment can improved the clinical manifestation and ventilation ,raise the curative effect of severe asthma.