全民食盐加碘前安徽大别山巢湖缺碘病区和合肥市儿童碘营养及甲状腺功能的研究

Studies on status of iodine nutrition and thyroid function of children from iodine-deficient areas in Dabie mountain and Chaohu district, and Hefei city before universal salt iodization

对安徽大别山、巢湖缺碘病区和合肥市共３７５９例儿童在全民食盐加碘前的碘营养、垂体—甲状腺轴功能状态进行研究。结果表明：巢湖组为重病区（肿大率为５５．８％），儿童人群严重缺碘（尿碘中位数为１９．２μｇ／Ｌ），垂体—甲状腺轴功能呈高代偿状态，有亚临床甲状腺功能减退存在。大别山组，尿碘（中位数２６９．１μｇ／Ｌ）虽高，但甲肿率为２２．４％，为中等病区水平，且垂体—甲状腺轴功能呈代偿状态，也提示有亚甲减存在，而合肥市甲肿率低，各项功能正常，为非病区，但尿碘水平偏低，提示碘营养不足。显示了全民食盐加碘防治的必要性。

Studies on status of iodine nutrition and hypoghysis-thyroid axis function of 3739 children were carrid out from iodine-deficient areas in Dabie moumtain and Chaohu district and Hefei city before universal salt iodization.The results showed that Chaohu was severe iodine-deficient area(TGR=55.8%,N ui =19.2μg/L),functional state of hypophysis-thyroid axis was highly compensatory,and there was Subclinic hypothyroidism . Dabie was moderate endemia(TGR=22.4%),hypophysis-thyroid axis was in compensative phase,and subclinic hypothyroidism also existed though median urinary iodine was higher .Hefei was non-IDD area(TGR was lower,and functional state was normal),but median urinary iodine was lower ,which indicated iodine-nutritional deficiency.These results suggested importance of universal salt iodization.